After being disgraced by a shady media publication, investigative journalist Eddie Brock's career is only headed in a downward spiral. However, destiny pushes him to interview Carlton Drake, a scientist who allegedly conducts secret experiments on humans in the name of discovering more about extraterrestrial life. During one of these experiments, an alien symbiote merges with Eddie's body, giving him extraterrestrial powers and abilities that empower him to fight crime on the streets of New York City. As he embraces his new powers and embraces the voice of the alien symbiote, Venom, inside his head, Eddie realizes that he must use his new powers to bring down the nefarious Drake and save the city from peril.