CIA Officer Evelyn Salt is accused of being a Russian sleeper spy. Just as she is on the verge of promotion, a suspicious encounter with a Russian courier causes her to go on the run, thrusting her into a dangerous game of cat and mouse with her alleged betrayers. Using all her intelligence and skills, she painstakingly reconstructs her own history, uncovering secrets that challenge everything she thought she knew about herself, and deduces that not everything is as it seems.