In the latest installment of the legendary survival horror franchise, three familiar characters from previous games gather in San Francisco as it suffers from a terrifying zombie outbreak. Police officer Leon Kennedy, former S.T.A.R.S. member Jill Valentine, and motorcycle courier Claire Redfield reunite to face a relentless group of killers, including a terrifying new T- Virus creation, creatures with twisted pasts and an evil, parasitic organism controlled by a mysterious organization controlling the zombies and spreading chaos.