Jai (John Abraham) and Ali (Shahid Kapoor) a mismatched odd couple of cops, come together once again to tackle a series of perplexing crimes and thwart the plans of a mysterious criminal organization planning to wreak havoc on Mumbai, a city under siege. Their quest to unravel the truth leads them on an adventurous journey spanning across many countries and many more dangers. Whether it's battling outlaws on a speeding train or trading bullets in fiery showdown, they must use every skill and resource they have to catch the elusive villain and prevent another catastrophe.