Acclaimed detective Byomkesh, fresh out of college, agrees to investigate the disappearance of Bhuvan, a chemist down on his luck, but he cannot seem to find any witnesses. However, Byomkesh is not one to give up and he persists in his investigation. Assisted by Bhuvan's son, Ajit, the duo link the case to a larger conspiracy that will unsettle Calcutta and bring forth a formidable opponent for our young detective. Will Byomkesh be able to solve the case and make it home alive?