In the investigative comedy 'Agent Sai Srinivasa Athreya,' the eponymous detective, along with his less-than-enthusiastic partner Kitty, runs a quirky agency called FBI (Famous Bureau of Investigation). When a mysterious stranger identifying himself as Hamilton seeks their help, Athreya finds himself entangled in a perplexing case that rivals the complexity of those tackled by Sherlock Holmes. Set in the underbelly of a small town in Andhra Pradesh, India, this lively caper unfolds a slew of humorous and mysterious events.